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Dickey’s lab started finding out mucin secretion 20 years back and previously recognized The real key genes and proteins included, exhibiting how synaptotagmin in addition to a SNARE complicated, much like that found in neurons, contribute to The important thing process of Ca2+-triggered membrane fusion.
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You'll be able to’t transfer air via an airway that’s plugged,” Dickey stated. “In bronchial asthma, COPD and CF, it’s been demonstrated that persistent plugs generate one of the most significant illness. Now We've a drug that may be very important if it’s proven to operate in clinical trials.”
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